Evaluation of biochemical marker for bone turnover in post menopausal women

Authors

Abstract

Introduction: Menopause is the permanent cessation of menses resulting from reduced ovarian hormone secretion that occurs naturally or is induced by surgery, chemotherapy, or radiation. Aims and objectives: To evaluate the risk of accelerated bone loss by assessing bone markers like alkaline phosphatase (ALP) and calcium in postmenopausal women. Material and methods: The present study was carried out on 100 total subjects out of which experimental group consists of 50 subjects i.e Post menopausal women. Control group consists of 50 subjects Pre menopausal women. Results: The result of the present study suggest that the serum calcium level were signifi cantly reduced but the serum alkaline phosphatase (ALP) levels had a slightly raise in post menopause group when compared to the pre menopause groups. Conclusion: In normal post menopausal women, an increase in bone turnover accelerates the reduction in bone mass, whereas decrease in bone turnover is associated with preservation of bone mass.

Downloads

Download data is not yet available.

Author Biographies

  • Keshab Raj Joshi, Lumbini Medical College

    Lecturer

    Department of Biochemistry

  • S P Devi, Lumbini Medical College
    Department of Biochemistry
  • P P Lanjikar, Lumbini Medical College
    Department of Biochemistry

Downloads

Published

2013-12-30

Issue

Vol. 1 No. 2 (2013)

Section

Original Research Article

License

  • The Journal of Lumbini Medical College (JLMC) publishes open access articles under the terms of the Creative Commons Attribution (CC BY) License which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  • JLMC requires an exclusive licence to publish the article first in its journal in print and online.
  • The corresponding author should read and agree to the following statement before submission of the manuscript for publication,
    • License agreement
    • In submitting an article to Journal of Lumbini Medical College (JLMC) I certify that:
      1. I am authorized by my co-authors to enter into these arrangements.
      2. I warrant, on behalf of myself and my co-authors, that:
        1. the article is original, has not been formally published in any other peer-reviewed journal, is not under consideration by any other journal and does not infringe any existing copyright or any other third party rights;
        2. I am/we are the sole author(s) of the article and have full authority to enter into this agreement and in granting rights to JLMC are not in breach of any other obligation;
        3. the article contains nothing that is unlawful, libellous, or which would, if published, constitute a breach of contract or of confidence or of commitment given to secrecy;
        4. I/we have taken due care to ensure the integrity of the article. To my/our - and currently accepted scientific - knowledge all statements contained in it purporting to be facts are true and any formula or instruction contained in the article will not, if followed accurately, cause any injury, illness or damage to the user.
      3. I, and all co-authors, agree that the article, if editorially accepted for publication, shall be licensed under the Creative Commons Attribution License 4.0. If the law requires that the article be published in the public domain, I/we will notify JLMC at the time of submission, and in such cases the article shall be released under the Creative Commons 1.0 Public Domain Dedication waiver. For the avoidance of doubt it is stated that sections 1 and 2 of this license agreement shall apply and prevail regardless of whether the article is published under Creative Commons Attribution License 4.0 or the Creative Commons 1.0 Public Domain Dedication waiver.
      4. I, and all co-authors, agree that, if the article is editorially accepted for publication in JLMC, data included in the article shall be made available under the Creative Commons 1.0 Public Domain Dedication waiver, unless otherwise stated. For the avoidance of doubt it is stated that sections 1, 2, and 3 of this license agreement shall apply and prevail.

                            Please visit Creative Commons web page for details of the terms.

How to Cite

1.
Evaluation of biochemical marker for bone turnover in post menopausal women. J Lumbini Med Coll [Internet]. 2013 Dec. 30 [cited 2026 Apr. 16];1(2):57-9. Available from: https://mail.jlmc.edu.np/index.php/JLMC/article/view/20